NIAID's HIV/AIDS Research Program

Although progress has been made in the global fight against HIV/AIDS, the epidemic continues to devastate the United States and the international community with 56,300 new HIV infections each year in the U.S. and an estimated 33 million people living with HIV worldwide. As the leading U.S. government institute for HIV/AIDS research, NIAID is committed to conducting the research necessary to successfully end the fight against HIV/AIDS.

Through laboratories and clinics on the NIH campus in Bethesda, Md., and a vast network of supported research at universities, medical centers and clinical trial sites around the globe, NIAID is working to better understand HIV and how it causes disease, find new tools to prevent HIV infection including a preventive vaccine, develop new and more effective treatments for people infected with HIV, and hopefully, find a cure.

HIV/AIDS Clinical Research

NIAID supports six clinical trial networks that conduct domestic and international human studies focused on the institute’s highest HIV/AIDS research priorities including:

  • New HIV prevention methods
  • Vaccine research and development
  • Microbicides to prevent HIV acquisition and transmission
  • Strategies to prevent mother-to-child HIV transmission
  • New drug development and optimizing clinical management of HIV/AIDS, including co-morbidities.          

The clinical trial networks include:
Each network consists of a clinical trial unit led by a principal investigator and features an administrative component, community advisory board and one or more clinical research sites, such as medical schools, academic health centers, hospitals or outpatient centers, where the clinical trials are performed. For a complete listing of all of the clinical trial units and sites, see: HIV/AIDS Network Clinical Trials Units (CTU) and Clinical Research Sites (CRS).

Vaccine Research Center Studies

In addition to the six HIV/AIDS clinical trial networks, NIAID also conducts early stage HIV vaccine research through its Dale and Betty Bumpers Vaccine Research Center (VRC) on the NIH campus in Bethesda, Md. The VRC Clinical Trials Core Laboratory performs Phase I human research of HIV vaccines developed at the VRC.
For information about current federally funded and privately sponsored HIV/AIDS clinical trials, see AIDSinfo or ClinicalTrials.gov.

Epidemiological Research

NIAID supports investigator-initiated epidemiological research as well as a number of targeted programs and several large HIV/AIDS epidemiological cohort studies.

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